TOXICOLOGY IN VITRO Q2区

期刊简介

Toxicology in Vitro publishes original research papers and reviews on the application and use of in vitro systems for assessing or predicting the toxic effects of chemicals and elucidating their mechanisms of action. These in vitro techniques include utilizing cell or tissue cultures, isolated cells, tissue slices, subcellular fractions, transgenic cell cultures, and cells from transgenic organisms, as well as in silico modelling. The Journal will focus on investigations that involve the development and validation of new in vitro methods, e.g. for prediction of toxic effects based on traditional and in silico modelling; on the use of methods in high-throughput toxicology and pharmacology; elucidation of mechanisms of toxic action; the application of genomics, transcriptomics and proteomics in toxicology, as well as on comparative studies that characterise the relationship between in vitro and in vivo findings. The Journal strongly encourages the submission of manuscripts that focus on the development of in vitro methods, their practical applications and regulatory use (e.g. in the areas of food components cosmetics, pharmaceuticals, pesticides, and industrial chemicals). Toxicology in Vitro discourages papers that record reporting on toxicological effects from materials, such as plant extracts or herbal medicines, that have not been chemically characterized.

《体外毒理学》发表了关于体外系统应用和使用的原创研究论文和评论，用于评估或预测化学品的毒性作用并阐明其作用机制。这些体外技术包括利用细胞或组织培养物、分离的细胞、组织切片、亚细胞级分、转基因细胞培养物和来自转基因生物体的细胞，以及计算机模拟。该杂志将侧重于涉及开发和验证新的体外方法的研究，例如，根据传统和计算机模拟预测毒性作用;在高通量毒理学和药理学中使用方法;阐明毒性作用机制;基因组学、转录组学和蛋白质组学在毒理学中的应用，以及表征体外和体内结果之间关系的比较研究。本杂志强烈鼓励投稿，重点关注体外方法的开发、实际应用和监管使用（例如，在食品成分、化妆品、药品、农药和工业化学品领域）。《体外毒理学》不鼓励发表关于未进行化学表征的材料（如植物提取物或草药）的毒理学效应报告的论文。

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