JOURNAL OF GENE MEDICINE（基因医学杂志）影响因子_期刊投稿发表

期刊简介

The aims and scope of The Journal of Gene Medicine include cutting-edge science of gene transfer and its applications in gene and cell therapy, genome editing with precision nucleases, epigenetic modifications of host genome by small molecules, siRNA, microRNA and other noncoding RNAs as therapeutic gene-modulating agents or targets, biomarkers for precision medicine, and gene-based prognostic/diagnostic studies.Key areas of interest are the design of novel synthetic and viral vectors, novel therapeutic nucleic acids such as mRNA, modified microRNAs and siRNAs, antagomirs, aptamers, antisense and exon-skipping agents, refined genome editing tools using nucleic acid /protein combinations, physically or biologically targeted delivery and gene modulation, ex vivo or in vivo pharmacological studies including animal models, and human clinical trials.Papers presenting research into the mechanisms underlying transfer and action of gene medicines, the application of the new technologies for stem cell modification or nucleic acid based vaccines, the identification of new genetic or epigenetic variations as biomarkers to direct precision medicine, and the preclinical/clinical development of gene/expression signatures indicative of diagnosis or predictive of prognosis are also encouraged.

《基因医学杂志》的宗旨和范围包括：基因转移的前沿科学及其在基因和细胞治疗中的应用，用精确核酸酶编辑基因组，用小分子、siRNA、microRNA和其他非编码RNA作为治疗性基因调节剂或靶点对宿主基因组进行表观遗传修饰，用于精确医学的生物标志物，以及基于基因的预后/诊断研究，感兴趣的关键领域是设计新的合成和病毒载体，新的治疗性核酸如mRNA、修饰的微小RNA和siRNA，拮抗剂，适体，反义和外显子跳跃剂，使用核酸/蛋白质组合的精细基因组编辑工具、物理或生物靶向递送和基因调节、离体或体内药理学研究（包括动物模型）和人类临床试验。介绍基因药物转移和作用机制研究的论文，干细胞修饰或基于核酸的疫苗的新技术的应用，新的遗传或表观遗传变异作为生物标志物的鉴定以指导精确医疗，并且还鼓励指示诊断或预测预后的基因/表达标记的临床前/临床开发。

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