1662-5099
3.5
否
不在预警名单内
是
Q2区
0
医学
SWITZERLAND
Frontiers Media S.A.
SCIE,Scopus,DOAJ开放期刊
706
120.02
-
Frontiers in Molecular Neuroscience is a first-tier electronic journal devoted to identifying key molecules, as well as their functions and interactions, that underlie the structure, design and function of the brain across all levels. The scope of our journal encompasses synaptic and cellular proteins, coding and non-coding RNA, and molecular mechanisms regulating cellular and dendritic RNA translation. In recent years, a plethora of new cellular and synaptic players have been identified from reduced systems, such as neuronal cultures, but the relevance of these molecules in terms of cellular and synaptic function and plasticity in the living brain and its circuits has not been validated. The effects of spine growth and density observed using gene products identified from in vitro work are frequently not reproduced in vivo. Our journal is particularly interested in studies on genetically engineered model organisms (C. elegans, Drosophila, mouse), in which alterations in key molecules underlying cellular and synaptic function and plasticity produce defined anatomical, physiological and behavioral changes. In the mouse, genetic alterations limited to particular neural circuits (olfactory bulb, motor cortex, cortical layers, hippocampal subfields, cerebellum), preferably regulated in time and on demand, are of special interest, as they sidestep potential compensatory developmental effects.
《分子神经科学前沿》(Frontiers in Molecular Neuroscience)是一本一流的电子期刊,致力于识别关键分子及其功能和相互作用,这些分子构成了大脑各个层面的结构、设计和功能的基础。我们杂志的范围包括突触和细胞蛋白质,编码和非编码RNA,以及调节细胞和树突RNA翻译的分子机制。近年来,从简化系统(如神经元培养物)中鉴定出了大量新的细胞和突触参与者,但这些分子在活脑及其回路中的细胞和突触功能以及可塑性方面的相关性尚未得到验证。使用从体外工作中鉴定的基因产物观察到的脊柱生长和密度的影响通常不能在体内再现。我们的杂志对基因工程模式生物的研究特别感兴趣。elegans、果蝇属、小鼠),其中细胞和突触功能和可塑性基础的关键分子的改变产生确定的解剖学、生理学和行为学变化。在小鼠中,限于特定神经回路(嗅球、运动皮质、皮质层、海马亚区、小脑)的遗传改变(优选地在时间上和按需调节)特别令人感兴趣,因为它们避开了潜在的补偿性发育效应。
《Frontiers in Molecular Neuroscience》期刊已被查看: 次
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