BIOPHARMACEUTICS & DRUG DISPOSITION Q4区

期刊简介

Biopharmaceutics & Drug Dispositionpublishes original review articles, short communications, and reports in biopharmaceutics, drug disposition, pharmacokinetics and pharmacodynamics, especially those that have a direct relation to the drug discovery/development and the therapeutic use of drugs. These includes:- animal and human pharmacological studies that focus on therapeutic response. pharmacodynamics, and toxicity related to plasma and tissue concentrations of drugs and their metabolites,- in vitro and in vivo drug absorption, distribution, metabolism, transport, and excretion studies that facilitate investigations related to the use of drugs in man- studies on membrane transport and enzymes, including their regulation and the impact of pharmacogenomics on drug absorption and disposition,- simulation and modeling in drug discovery and development- theoretical treatises- includes themed issues and reviewsand exclude manuscripts on- bioavailability studies reporting only on simple PK parameters such as Cmax, tmax and t1/2 without mechanistic interpretation- analytical methods

生物药剂学与药物处置发表生物药剂学、药物处置、药代动力学和药效学方面的原创综述文章、短通讯和报告，特别是与药物发现/开发和药物治疗使用直接相关的文章。这些研究包括：-关注治疗反应的动物和人体药理学研究。药效学和与药物及其代谢物的血浆和组织浓度相关的毒性，-体外和体内药物吸收、分布、代谢、转运和排泄研究，其促进与药物在人体中的使用相关的研究-对膜转运和酶的研究，包括它们的调节和药物基因组学对药物吸收和处置的影响，- 药物发现和开发中的模拟和建模-理论论文-包括主题问题和综述，但不包括手稿-仅报告简单PK参数（如Cmax、tmax和t1/2）而无机制解释的生物利用度研究-分析方法

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